{"id":94848,"date":"2023-11-08T13:50:00","date_gmt":"2023-11-08T05:50:00","guid":{"rendered":"https:\/\/gothe.tw\/?p=94848"},"modified":"2023-11-08T13:50:00","modified_gmt":"2023-11-08T05:50:00","slug":"%e5%86%8d%e9%bc%8e%e9%86%ab%e8%97%a5%e5%85%ac%e5%b8%832023%e5%b9%b4%e7%ac%ac%e4%b8%89%e5%ad%a3%e5%ba%a6%e8%b2%a1%e5%8b%99%e6%a5%ad%e7%b8%be%e5%92%8c%e5%85%ac%e5%8f%b8%e9%80%b2%e5%b1%95","status":"publish","type":"post","link":"https:\/\/gothe.tw\/?p=94848","title":{"rendered":"\u518d\u9f0e\u91ab\u85e5\u516c\u5e032023\u5e74\u7b2c\u4e09\u5b63\u5ea6\u8ca1\u52d9\u696d\u7e3e\u548c\u516c\u53f8\u9032\u5c55"},"content":{"rendered":"<div>\n<div>\n<ul 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Smiley\u8868\u793a\uff1a\u300c\u6211\u5011\u7684\u5546\u696d\u5316\u5718\u968a\u9762\u5c0d\u7b2c\u4e09\u5b63\u5ea6\u5b8f\u89c0\u5c64\u9762\u7684\u6311\u6230\uff0c\u4ecd\u5be6\u73fe\u4e86\u540c\u6bd427%\u7684\u7522\u54c1\u6de8\u6536\u5165\u589e\u9577\uff08\u4ee5\u56fa\u5b9a\u532f\u7387\u8a08\u7b97\uff09\u3002\u5247\u6a02\u4ecd\u7136\u662f\u4e2d\u570b\u5167\u5730\u5375\u5de2\u764c\u9818\u57df\u9662\u5167\u92b7\u552e\u9818\u5148PARP\u6291\u5236\u5291\uff1b\u4f5c\u70ba\u4e00\u6b3e\u6709\u671b\u6539\u8b8a\u4e2d\u570b gMG 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type=\"disc\">\n<li>2023\u5e74\u7b2c\u4e09\u5b63\u5ea6\u7684<b>\u7522\u54c1\u6536\u5165<\/b>\u70ba6,920\u842c\u7f8e\u5143\uff0c2022\u5e74\u540c\u671f\u70ba5,700\u842c\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957722%\uff0c\u6309\u56fa\u5b9a\u532f\u7387\u8a08\u7b97\u540c\u6bd4\u589e\u957727%\u3002\u7522\u54c1\u6536\u5165\u589e\u52a0\u4e3b\u8981\u662f\u7531\u65bc\u92b7\u91cf\u7684\u589e\u52a0\u3001\u885b\u5049\u8fe6\u7684\u4e0a\u5e02\u4ee5\u53caCOVID-19\u75ab\u60c5\u8ca0\u9762\u5f71\u97ff\u7684\u6e1b\u5c11\u3002\u4e2d\u570b\u8fd1\u671f\u91ab\u85e5\u653f\u7b56\u74b0\u5883\u7684\u8abf\u6574\u7d66\u91ab\u9662\u53ca\u91ab\u751f\u57f7\u696d\u5e36\u4f86\u4e00\u5b9a\u5f71\u97ff\u4f7f\u516c\u53f8\u7684\u6536\u5165\u589e\u9577\u653e\u7de9\u3002\u82072022\u5e74\u540c\u671f\u76f8\u6bd4\uff0c2023\u5e74\u7b2c\u4e09\u5b63\u5ea6\u7684\u7522\u54c1\u6536\u5165\u5305\u62ec\uff1a<\/li>\n<li style=\"list-style-type: none;\">\n<ul 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\/>\u00a0<\/li>\n<li>\u622a\u81f32023\u5e749\u670830\u65e5\uff0c<b>\u73fe\u91d1\u53ca\u73fe\u91d1\u7b49\u50f9\u7269\u3001\u77ed\u671f\u6295\u8cc7\u548c\u53d7\u9650\u5236\u73fe\u91d1<\/b>\u7e3d\u8a08\u70ba8.222\u5104\u7f8e\u5143\uff0c\u622a\u81f32023\u67086\u670830\u65e5\u5176\u70ba8.764\u5104\u7f8e\u5143\u3002<\/li>\n<\/ul>\n<p><b><u>\u8fd1\u671f\u7522\u54c1\u4eae\u9ede\u548c\u516c\u53f8\u9032\u5c55<\/u><\/b><\/p>\n<p>\u81ea\u4e0a\u6b21\u8ca1\u5831\u767c\u5e03\u4ee5\u4f86\u518d\u9f0e\u91ab\u85e5\u4e3b\u8981\u7522\u54c1\u548c\u516c\u53f8\u9032\u5c55\u5305\u62ec\uff1a<\/p>\n<p><b><i>\u5546\u696d\u5316\u7522\u54c1<\/i><\/b><\/p>\n<ul type=\"disc\">\n<li><b>\u885b\u5049\u8fe6\uff08\u827e\u52a0\u83ab\u5fb7\uff0c<\/b><b>FcRn<\/b><b>\uff09<\/b>\uff1a2023\u5e749\u6708\uff0c\u885b\u5049\u8fe6\u65bc\u4e2d\u570b\u5167\u5730\u4e0a\u5e02\uff0c\u8207\u5e38\u898f\u6cbb\u7642\u85e5\u7269\u806f\u5408\uff0c\u7528\u65bc\u6cbb\u7642\u4e59\u9170\u81bd\u9e7c\uff08AChR\uff09\u6297\u9ad4\u967d\u6027\u7684\u6210\u4ebagMG\u60a3\u8005\u3002\u518d\u9f0e\u91ab\u85e5\u7684\u5546\u696d\u5316\u7522\u54c1\u6578\u91cf\u589e\u52a0\u52305\u6b3e\u3002\u518d\u9f0e\u91ab\u85e5\u6b63\u52aa\u529b\u5c07\u885b\u5049\u8fe6\u7d0d\u5165NRDL\uff0c\u8b93\u9019\u4e00\u7642\u6cd5\u53ef\u4ee5\u60e0\u53ca\u66f4\u591a\u60a3\u8005\u3002<br \/>\u00a0<\/li>\n<li><b>\u5247\u6a02\uff08\u5c3c\u62c9\u5e15\u5229\uff0c<\/b><b>PARP<\/b><b>\uff09<\/b>\uff1a2023\u5e749\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5c0d\u5728\u4e2d\u570b\u9251\u654f\u611f\u5fa9\u767c\u6027\u5375\u5de2\u764c\u60a3\u8005\u4e2d\u958b\u5c55\u76843\u671fNORA\u7814\u7a76\u9032\u884c\u4e86\u6700\u7d42\u7e3d\u751f\u5b58\u671f\uff08OS\uff09\u5206\u6790\uff0c\u5206\u6790\u7d50\u679c\u9032\u4e00\u6b65\u652f\u6301\u4e86NMPA\u5c0d\u5247\u6a02\u5728\u4e2d\u570b\u7528\u65bc\u9251\u654f\u611f\u5fa9\u767c\u6027\u5375\u5de2\u764c\u60a3\u8005\u7684\u6279\u51c6\u3002\u6700\u7d42OS\u7d50\u679c\u986f\u793a\uff0c\u7121\u8ad6\u60a3\u8005gBRCA\u7a81\u8b8a\u72c0\u614b\u5982\u4f55\uff0c\u8207\u5b89\u6170\u5291\u76f8\u6bd4\uff0c\u5c3c\u62c9\u5e15\u5229\u7528\u65bc\u5fa9\u767c\u7dad\u6301\u6cbb\u7642\u8868\u73fe\u51fa\u4e86\u80fd\u5920\u5ef6\u9577\u60a3\u8005\u7e3d\u751f\u5b58\u671f\uff08OS\uff09\u7684\u6709\u5229\u8da8\u52e2\u3002\u6211\u5011\u671f\u5f85\u5728\u5373\u5c07\u53ec\u958b\u7684\u91ab\u5b78\u6703\u8b70\u4e0a\u516c\u5e03\u8a73\u7d30\u7d50\u679c\u3002<\/li>\n<\/ul>\n<p><b><i>\u816b\u7624\u9818\u57df\u7ba1\u7dda<\/i><\/b><\/p>\n<ul type=\"disc\">\n<li><b>KRAZATI<sup>\u00ae<\/sup>\u00a0(adagrasib,\u00a0KRAS<sup>G12C<\/sup>):<\/b><\/li>\n<ul type=\"circle\">\n<li><i>\u4e00\u7dda\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08<\/i><i>NSCLC<\/i><i>\uff09\uff1a<\/i>2023\u5e7410\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u4f19\u4f34Mirati Therapeutics\uff08Mirati\uff09\u57282023\u5e74\u6b50\u6d32\u816b\u7624\u5167\u79d1\u5b78\u6703\uff08ESMO\uff09\u5927\u6703\u4e0a\u516c\u5e03\u4e86KRYSTAL-7 2\u671f\u7814\u7a76\u7684\u6700\u65b0\u7d50\u679c\uff0c\u8a72\u7814\u7a76\u8a55\u4f30\u4e86adagrasib\u806f\u5408\u5e15\u535a\u5229\u73e0\u55ae\u6297\u4e00\u7dda\u6cbb\u7642\u651c\u5e36KRAS<sup>G12C<\/sup>\u7a81\u8b8a\u7684NSCLC\u60a3\u8005\u3002\u7d50\u679c\u8868\u660e\uff0cadagrasib\u8207\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u806f\u5408\u4e00\u7dda\u6cbb\u7642NSCLC\u5177\u6709\u53ef\u63a7\u7684\u5b89\u5168\u6027\u548c\u6301\u4e45\u7642\u6548\u7684\u521d\u6b65\u4fe1\u865f\u3002\u518d\u9f0e\u91ab\u85e5\u5728\u4e2d\u570b\u5167\u5730\u3001\u9999\u6e2f\u3001\u6fb3\u9580\u548c\u53f0\u7063\u5730\u5340\uff08\u7d71\u7a31\u70ba\u5927\u4e2d\u83ef\u5340\uff09\u53c3\u8207\u4e86\u8a72\u7814\u7a76\u3002<br \/>\u00a0<\/li>\n<li><i>\u4e8c\u7dda\u53ca\u4ee5\u4e0a<\/i><i>NSCLC<\/i>\uff1a2023\u5e749\u6708\uff0cMirati\u57282023\u5e74\u4e16\u754c\u80ba\u764c\u5927\u6703\uff08WCLC\uff09\u4e0a\u516c\u5e03\u4e86KRYSTAL-1\u7814\u7a76\u76841\/1b\u671f\u968a\u5217\u548c2\u671f\u968a\u5217A\u532f\u7e3d\u5206\u6790\u7684\u5169\u5e74\u96a8\u8a2a\u6578\u64da\uff0c\u8a72\u7814\u7a76\u91dd\u5c0d\u7d93\u6cbb\u7684KRAS<sup>G12C<\/sup>\u7a81\u8b8aNSCLC\u60a3\u8005\u3002\u5728\u532f\u7e3d\u5206\u6790\u4e2d\uff0cadagrasib\u986f\u793a\u51fa\u6301\u4e45\u7684\u7642\u6548\u548c\u53ef\u63a7\u7684\u9577\u671f\u5b89\u5168\u6027\u3002\u6211\u5011\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u5c0d\u7d93\u6cbb\u7684KRAS<sup>G12C<\/sup>\u7a81\u8b8aNSCLC\u60a3\u8005\u9032\u884c\u7684KRYSTAL-12 3\u671f\u9a57\u8b49\u6027\u7814\u7a76\u3002<br \/>\u00a0<\/li>\n<\/ul>\n<li><b>\u745e\u666e\u66ff\u5c3c\uff08<\/b><b>ROS1\/TRK<\/b><b>\uff09\uff1a<\/b><\/li>\n<ul type=\"circle\">\n<li><i>NTRK<\/i><i>\u967d\u6027\u5be6\u9ad4\u7624<\/i>\uff1a2023\u5e748\u6708\uff0cNMPA\u85e5\u54c1\u5be9\u8a55\u4e2d\u5fc3\uff08CDE\uff09\u6388\u4e88\u745e\u666e\u66ff\u5c3c\u7a81\u7834\u6027\u6cbb\u7642\u8a8d\u5b9a\uff08BTD\uff09\uff0c\u7528\u65bc\u6cbb\u7642NTRK\u57fa\u56e0\u878d\u5408\u7684\u665a\u671f\u5be6\u9ad4\u7624\u60a3\u8005\uff0c\u9019\u4e9b\u60a3\u8005\u5728\u63a5\u53d7TRK\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5291\uff08TKIs\uff09\u6cbb\u7642\u5f8c\u75c5\u60c5\u51fa\u73fe\u9032\u5c55\u3002\u8a72BTD\u662f\u57fa\u65bc1\/2\u671fTRIDENT-1\u7814\u7a76\u4e2d\u5168\u7403\u548c\u4e2d\u570b\u5165\u7d44\u60a3\u8005\u7684\u6578\u64da\u652f\u6301\u3002<br \/>\u00a0<\/li>\n<li><i>ROS1<\/i><i>\u967d\u6027<\/i><i>NSCLC<\/i>\uff1a2023\u5e748\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u4f19\u4f34\u767e\u6642\u7f8e\u65bd\u8cb4\u5bf6\uff08BMS\uff09\u516c\u5e03\u4e86\u6ce8\u518a\u6027\u7814\u7a76TRIDENT-1\u7684\u6700\u65b0\u7d50\u679c\uff0c\u91dd\u5c0dTKI\u521d\u6cbb\u6216\u65e2\u5f80\u63a5\u53d7\u904e\u4e00\u7a2eTKI\u4e14\u672a\u63a5\u53d7\u904e\u5316\u7642\u7684ROS1\u967d\u6027\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027NSCLC\u60a3\u8005\uff0c\u745e\u666e\u66ff\u5c3c\u7e7c\u7e8c\u8b49\u5be6\u5177\u6709\u9ad8\u61c9\u7b54\u7387\u548c\u6301\u4e45\u61c9\u7b54\uff0c\u5305\u62ec\u826f\u597d\u7684\u9871\u5167\u61c9\u7b54\u3002\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u9019\u9805\u7814\u7a76\u3002<br \/>\u00a0<\/li>\n<ul type=\"square\">\n<li>\u6839\u64daTRIDENT-1\u7814\u7a76\u7684\u7d50\u679c\uff0c\u7f8e\u570b\u98df\u54c1\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u53d7\u7406\u4e86BMS\u63d0\u4ea4\u7684\u745e\u666e\u66ff\u5c3c\u7528\u65bcROS1\u967d\u6027NSCLC\u7684\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\uff08NDA\uff09\uff0c\u4e26\u6388\u4e88\u5176\u512a\u5148\u5be9\u8a55\u8cc7\u683c\u3002\u8655\u65b9\u85e5\u7528\u6236\u4ed8\u8cbb\u65b9\u6848\uff08PDUFA\uff09\u76ee\u6a19\u884c\u52d5\u65e5\u671f\u70ba2023\u5e7411\u670827\u65e5\u3002<br \/>\u00a0<\/li>\n<li>\u518d\u9f0e\u91ab\u85e5\u5411NMPA\u63d0\u4ea4\u7684\u745e\u666e\u66ff\u5c3c\u7528\u65bcROS1\u967d\u6027NSCLC\u7684NDA\u5df2\u88ab\u53d7\u7406\u4e26\u6388\u4e88\u512a\u5148\u5be9\u8a55\u8cc7\u683c\u3002<br \/>\u00a0<\/li>\n<\/ul>\n<\/ul>\n<li><b>TIVDAK<sup>\u00ae<\/sup><\/b><b>\uff08<\/b><b>tisotumab vedotin<\/b><b>\uff09\uff1a<\/b>2023\u5e7410\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u4f19\u4f34Seagen Inc.\u548cGenmab A\/S \u57282023\u5e74ESMO \u5927\u6703\u4e0a\u516c\u5e03\u4e86\u5168\u74033\u671f\u96a8\u6a5f\u81e8\u5e8a\u7814\u7a76innovaTV 301\u7684\u7d50\u679c\uff0c\u7814\u7a76\u986f\u793a\uff0c\u8207\u55ae\u7368\u5316\u7642\u76f8\u6bd4\uff0c\u5728\u7cfb\u7d71\u6cbb\u7642\u671f\u9593\u6216\u6cbb\u7642\u5f8c\u767c\u751f\u75be\u75c5\u9032\u5c55\u7684\u5fa9\u767c\u6027\u6216\u8f49\u79fb\u6027\u5bae\u9838\u764c\u60a3\u8005\u4e2d\uff0c\u63a5\u53d7TIVDAK\u6cbb\u7642\u7684\u60a3\u8005\u986f\u8457\u5730\u6539\u5584\u4e86OS\u3001\u7121\u9032\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u548c\u5ba2\u89c0\u7de9\u89e3\u7387\uff0c\u4e14\u672a\u89c0\u5bdf\u5230\u65b0\u7684\u5b89\u5168\u6027\u4fe1\u865f\u3002\u6211\u5011\u53c3\u8207\u4e86\u8a72\u5168\u7403\u7814\u7a76\uff0c\u4e26\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u958b\u5c55\u64f4\u5c55\u7814\u7a76\u3002<br \/>\u00a0<\/li>\n<li><b>Odronextamab<\/b><b>\uff08<\/b><b>CD20xCD3<\/b><b>\uff09\uff1a<\/b>2023\u5e749\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u4f19\u4f34\u518d\u751f\u5143\u5ba3\u5e03\uff0cFDA\u5df2\u53d7\u7406odronextamab\u7684\u751f\u7269\u5236\u54c1\u8a31\u53ef\u7533\u8acb\uff08BLA\uff09\u4e26\u5c07\u5176\u7d0d\u5165\u512a\u5148\u5be9\u8a55\uff0c\u7528\u65bc\u6cbb\u7642\u6b64\u524d\u81f3\u5c11\u5169\u6b21\u5168\u8eab\u6cbb\u7642\u5f8c\u767c\u751f\u9032\u5c55\u7684\u5fa9\u767c\/\u96e3\u6cbb\u6027\uff08R\/R\uff09\u6ffe\u6ce1\u6027\u6dcb\u5df4\u7624\uff08FL\uff09\u6216R\/R\u5f4c\u6f2b\u6027\u5927B\u7d30\u80de\u6dcb\u5df4\u7624\uff08DLBCL\uff09\u7684\u6210\u5e74\u60a3\u8005\uff0cPDUFA\u76ee\u6a19\u884c\u52d5\u65e5\u671f\u70ba2024\u5e743\u670831\u65e5\u30022023\u5e748\u6708\uff0c\u6b50\u6d32\u85e5\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u53d7\u7406\u4e86odronextamab\u76f8\u540c\u9069\u61c9\u8b49\u7684\u4e0a\u5e02\u7533\u8acb\u3002<br \/>\u00a0<\/li>\n<li><b>ZL-1211<\/b><b>\uff08<\/b><b>Claudin18.2<\/b><b>\uff09\uff1a<\/b>\u57fa\u65bc\u5c0d\u7af6\u722d\u683c\u5c40\u548c\u5e02\u5834\u524d\u666f\u7684\u8a55\u4f30\uff0c\u6211\u5011\u6c7a\u5b9a\u7d42\u6b62ZL-1211\u7684\u5167\u90e8\u958b\u767c\u3002<br \/>\u00a0<\/li>\n<li><b>\u816b\u7624\u96fb\u5834\u6cbb\u7642\uff1a<\/b>2023\u5e748\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u4f19\u4f34NovoCure Limited\u5ba3\u5e03\uff0c\u816b\u7624\u96fb\u5834\u6cbb\u7642\u8207\u7d2b\u6749\u9187\u806f\u5408\u6cbb\u7642\u9251\u8010\u85e5\u5375\u5de2\u764c\u60a3\u8005\u76843\u671f\u81e8\u5e8a\u7814\u7a76INNOVATE-3\u7684\u6700\u7d42\u5206\u6790\u672a\u9054\u5230\u7e3d\u751f\u5b58\u671f\u9019\u4e00\u4e3b\u8981\u7d42\u9ede\u3002\u518d\u9f0e\u91ab\u85e5\u672a\u53c3\u8207\u9019\u4e00\u7814\u7a76\u00a0<\/li>\n<\/ul>\n<p><b><i>\u81ea\u8eab\u514d\u75ab\u75be\u75c5\u3001\u611f\u67d3\u6027\u75be\u75c5\u548c\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\u75be\u75c5\u9818\u57df\u7ba1\u7dda<\/i><\/b><\/p>\n<ul type=\"disc\">\n<li><b>\u827e\u52a0\u83ab\u5fb7\uff08<\/b><b>FcRn)<\/b><b>\uff1a<\/b>2023\u5e749\u6708\uff0cNMPA\u85e5\u54c1\u5be9\u8a55\u4e2d\u5fc3\u6388\u4e88\u827e\u52a0\u83ab\u5fb7\u03b1\u6ce8\u5c04\u6db2\uff08\u76ae\u4e0b\u6ce8\u5c04\uff09BTD\uff0c\u7528\u65bc\u6cbb\u7642\u6162\u6027\u708e\u6027\u812b\u9ad3\u9798\u6027\u591a\u767c\u6027\u795e\u7d93\u6839\u795e\u7d93\u75c5\uff08CIDP\uff09\u60a3\u8005\u3002\u8a72BTD\u662f\u57fa\u65bcADHERE\u7814\u7a76\u4e2d\u5168\u7403\u548c\u4e2d\u570b\u5165\u7d44\u60a3\u8005\u967d\u6027\u6578\u64da\u7684\u652f\u6301\u3002<br \/>\u00a0<\/li>\n<li><b>KarXT (xanomeline-trospium<\/b><b>\uff0c<\/b><b>M1\/M4<\/b><b>\u578b\u6bd2\u8548\u9e7c\u4e59\u9170\u81bd\u9e7c\u53d7\u9ad4\u6fc0\u52d5\u5291<\/b><b>)<\/b><\/li>\n<ul type=\"circle\">\n<li><i>\u7cbe\u795e\u5206\u88c2\u75c7\uff1a<\/i>2023\u5e749\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u4f19\u4f34Karuna Therapeutics, Inc. (Karuna)\u5ba3\u5e03\uff0c\u57fa\u65bc\u4e09\u9805\u6ce8\u518a\u6027\u7814\u7a76\u7684\u967d\u6027\u6578\u64da\uff0c\u5df2\u5411FDA\u63d0\u4ea4\u4e86\u7528\u65bc\u7cbe\u795e\u5206\u88c2\u75c7\u7684\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u3002\u518d\u9f0e\u91ab\u85e5\u5c07\u7e7c\u7e8c\u70ba\u4e2d\u570b\u5167\u5730\u7684\u6ce8\u518a\u6027\u6a4b\u63a5\u7814\u7a76\u62db\u52df\u60a3\u8005\u3002<br \/>\u00a0<\/li>\n<li><i>\u963f\u723e\u8328\u6d77\u9ed8\u75c7\u7cbe\u795e\u75c5\u6027\u969c\u7919\uff08<\/i><i>ADP<\/i><i>\uff09\uff1a<\/i>Karuna\u5728\u7b2c\u4e09\u5b63\u5ea6\u555f\u52d5\u4e86\u7528\u65bcADP\u76843\u671f\u81e8\u5e8a\u7814\u7a76ADEPT-2\u548c<i>ADEPT-3<\/i>\u3002\u518d\u9f0e\u91ab\u85e5\u8a08\u5283\u660e\u5e74\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u9019\u4e9b\u7814\u7a76\u3002<\/li>\n<\/ul>\n<\/ul>\n<p><b><i>\u516c\u53f8\u9032\u5c55<\/i><\/b><\/p>\n<ul type=\"disc\">\n<li><b>\u7d44\u7e54\u66f4\u65b0\uff1a<\/b>2023\u5e749\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u4efb\u547dRobert J. Brown\u535a\u58eb\u70ba\u816b\u7624\u9818\u57df\u9996\u5e2d\u91ab\u5b78\u5b98\u3002Brown\u535a\u58eb\u662f\u816b\u7624\u85e5\u7269\u958b\u767c\u7684\u9818\u5c0e\u8005\uff0c\u64c1\u6709\u8d85\u904e\u00a016 \u5e74\u7684\u8f49\u5316\u3001\u7814\u7a76\u548c\u81e8\u5e8a\u958b\u767c\u5c08\u696d\u7d93\u9a57\u3002Brown\u535a\u58eb\u5c07\u5411\u518d\u9f0e\u91ab\u85e5\u7e3d\u88c1\u517c\u5168\u7403\u816b\u7624\u7814\u767c\u8ca0\u8cac\u4ebaRafael Amado\u535a\u58eb\u532f\u5831\uff0c\u4e26\u70ba\u6211\u5011\u816b\u7624\u7ba1\u7dda\u7684\u81e8\u5e8a\u958b\u767c\u63d0\u4f9b\u6230\u7565\u9818\u5c0e\u548c\u652f\u6301\u3002<\/li>\n<\/ul>\n<p><b><u>2023\/2024<\/u><\/b><b><u>\u5e74\u7684\u9810\u671f\u91cd\u8981\u88e1\u7a0b\u7891\u4e8b\u4ef6<\/u><\/b><\/p>\n<p><b><i>\u816b\u7624\u9818\u57df<\/i><\/b><\/p>\n<p><b>\u5247\u6a02\uff08\u5c3c\u62c9\u5e15\u5229\uff0c<\/b><b>PARP<\/b><b>\uff09<\/b><\/p>\n<ul type=\"disc\">\n<li>\u518d\u9f0e\u91ab\u85e5\u5c07\u57282024\u5e74\u8209\u884c\u7684\u91ab\u5b78\u6703\u8b70\u4e0a\u516c\u5e03\u5728\u4e2d\u570b\u9251\u654f\u611f\u5fa9\u767c\u6027\u5375\u5de2\u764c\u60a3\u8005\u4e2d\u958b\u5c55\u76843\u671fNORA\u7814\u7a76\u6700\u7d42OS\u5206\u6790\u7d50\u679c\u3002<\/li>\n<\/ul>\n<p>\u00a0<b>\u816b\u7624\u96fb\u5834\u6cbb\u7642<\/b><\/p>\n<ul type=\"disc\">\n<li>NovoCure\u5c07\u65bc2023\u5e74\u5e74\u5e95\u524d\u5411FDA\u63d0\u4ea4\u816b\u7624\u96fb\u5834\u6cbb\u7642\u7528\u65bc\u9251\u985e\u5316\u7642\u5f8c\u51fa\u73fe\u9032\u5c55\u7684\u4e8c\u7dda\u53ca\u4ee5\u4e0aNSCLC\u60a3\u8005\u7684\u4e0a\u5e02\u524d\u6279\u51c6\u7533\u8acb\u3002<\/li>\n<li>NovoCure\u5c07\u65bc2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u516c\u5e03\u816b\u7624\u96fb\u5834\u6cbb\u7642\u7528\u65bc\u8166\u8f49\u79fb\u60a3\u8005\u76843\u671f\u81e8\u5e8a\u7814\u7a76METIS\u7684\u4e3b\u8981\u6578\u64da\u3002\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u9019\u9805\u7814\u7a76\u3002<\/li>\n<li>NovoCure\u5c07\u57282024\u5e74\u4e0b\u534a\u5e74\u516c\u5e03\u816b\u7624\u96fb\u5834\u6cbb\u7642\u7528\u65bc\u5c40\u90e8\u665a\u671f\u80f0\u817a\u764c\u76843\u671f\u81e8\u5e8a\u7814\u7a76PANOVA-3\u7684\u4e3b\u8981\u6578\u64da\u3002\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u9019\u9805\u7814\u7a76\u3002<\/li>\n<\/ul>\n<p>\u00a0<b>\u745e\u666e\u66ff\u5c3c\uff08<\/b><b>ROS1\/TRK<\/b><b>\uff09<\/b><\/p>\n<ul type=\"disc\">\n<li>\u745e\u666e\u66ff\u5c3c\u7528\u65bc\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027ROS1\u967d\u6027NSCLC\u7684\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\uff0c\u6709\u671b\u65bc2024\u5e74\u7372\u5f97NMPA\u6279\u51c6\u3002<\/li>\n<\/ul>\n<p><b>KRAZATI (adagrasib, KRAS<sup>G12C<\/sup>)<\/b><\/p>\n<ul type=\"disc\">\n<li>\u518d\u9f0e\u91ab\u85e5\u5c07\u65bc2024\u5e74\u5411NMPA\u63d0\u4ea4adagrasib\u7528\u65bc\u4e8c\u7dda\u53ca\u4ee5\u4e0aKRAS<sup>G12C<\/sup>\u7a81\u8b8aNSCLC\u7684\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u3002<\/li>\n<\/ul>\n<p><b>Bemarituzumab (FGFR2b)<\/b><\/p>\n<ul type=\"disc\">\n<li>\u518d\u9f0e\u91ab\u85e5\u5c07\u65bc2024\u5e74\u4e0a\u534a\u5e74\u5728\u5927\u4e2d\u83ef\u5340\u52a0\u5165bemarituzumab\u806f\u5408\u7d0d\u6b66\u5229\u5c24\u55ae\u6297\u548c\u5316\u7642\u7528\u65bc\u4e00\u7dda\u6cbb\u7642\u80c3\u764c\u6216\u80c3\u98df\u7ba1\u4ea4\u754c\u8655\u764c\u7684\u5168\u74033\u671f\u7814\u7a76FORTITUDE-102\u3002<\/li>\n<\/ul>\n<p><b>ZL-1310 (DLL3 ADC)<\/b><\/p>\n<ul type=\"disc\">\n<li>\u518d\u9f0e\u91ab\u85e5\u5c07\u65bc2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u555f\u52d5\u4e00\u9805ZL-1310\u7528\u65bc\u6cbb\u7642\u542b\u9251\u5316\u7642\u65b9\u6848\u6cbb\u7642\u5f8c\u51fa\u73fe\u9032\u5c55\u7684\u4e8c\u7dda\u53ca\u4ee5\u4e0a\u5fa9\u767c\u548c\u96e3\u6cbb\u6027\u5c0f\u7d30\u80de\u80ba\u764c\uff08SCLC\uff09\u7684\u5168\u74031\u671f\u7814\u7a76\u3002<\/li>\n<\/ul>\n<p><b><i>\u81ea\u8eab\u514d\u75ab\u75be\u75c5\u3001\u611f\u67d3\u6027\u75be\u75c5\u548c\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\u75be\u75c5\u9818\u57df<\/i><\/b><\/p>\n<p><b>\u827e\u52a0\u83ab\u5fb7<\/b><b>\u00a0(FcRn)<\/b><\/p>\n<ul type=\"disc\">\n<li>\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u4f19\u4f34\u00a0argenx\u5c07\u65bc2023 \u5e74\u7b2c\u56db\u5b63\u5ea6\u516c\u5e03\u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5291\u578b\u7528\u65bc\u6cbb\u7642\u514d\u75ab\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\uff08ITP\uff09\u7684\u6ce8\u518a\u60273 \u671f\u7814\u7a76ADVANCE-SC\u7684\u95dc\u9375\u6027\u6578\u64da\u3002\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u9019\u9805\u7814\u7a76\u3002<br \/>\u00a0<\/li>\n<li>argenx\u5c07\u65bc2023\u5e74\u5e74\u5e95\u5de6\u53f3\u516c\u5e03\u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5291\u578b\u7528\u65bc\u6cbb\u7642\u5929\u76b0\u7621\u7684\u6ce8\u518a\u6027\u00a03 \u671f\u7814\u7a76ADDRESS\u7684\u95dc\u9375\u6027\u6578\u64da\u3002\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u9019\u9805\u7814\u7a76\u3002<br \/>\u00a0<\/li>\n<li>argenx \u5c07\u5728\u00a02023 \u5e74\u5e74\u5e95\u4e4b\u524d\u63d0\u4ea4\u827e\u52a0\u83ab\u5fb7\u6cbb\u7642CIDP\u7684\u88dc\u5145\u00a0BLA\u3002<br \/>\u00a0<\/li>\n<li>argenx\u5c07\u65bc2023\u5e74\u7b2c\u56db\u5b63\u5ea6\u555f\u52d5\u827e\u52a0\u83ab\u5fb7\u6cbb\u7642\u7532\u72c0\u817a\u773c\u75c5\uff08TED\uff09\u7684\u6ce8\u518a\u6027\u7814\u7a76\u3002\u518d\u9f0e\u91ab\u85e5\u8a08\u52832024\u5e74\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u9019\u4e00\u9805\u76ee\u3002<br \/>\u00a0<\/li>\n<li>\u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5291\u578b\u7528\u65bcgMG\u7684\u88dc\u5145BLA\u6709\u671b\u65bc2024\u5e74\u7372NMPA\u6279\u51c6\u3002<\/li>\n<\/ul>\n<p><b>KarXT\u00a0<\/b><b>(xanomeline-trospium<\/b><b>\uff0c<\/b><b>M1\/M4<\/b><b>\u578b\u6bd2\u8548\u9e7c\u4e59\u9170\u81bd\u9e7c\u53d7\u9ad4\u6fc0\u52d5\u5291<\/b><b>)<\/b><\/p>\n<ul type=\"disc\">\n<li>\u5982KarXT\u7528\u65bc\u7cbe\u795e\u5206\u88c2\u75c7\u7684\u4e0a\u5e02\u7533\u8acb\u7372\u5f97FDA\u6279\u51c6\uff0cKaruna\u5c07\u65bc2024\u5e74\u4e0b\u534a\u5e74\u4e0a\u5e02KarXT\u3002<\/li>\n<\/ul>\n<p><b>XACDURO<sup>\u00ae<\/sup><\/b><b>\uff08\u8212\u5df4\u5766\u9209<\/b><b>\u2013<\/b><b>\u5ea6\u6d1b\u5df4\u5766\u9209\uff09<\/b><\/p>\n<ul type=\"disc\">\n<li>\u8212\u5df4\u5766\u9209-\u5ea6\u6d1b\u5df4\u5766\u9209\u7528\u65bc\u7531\u9b91\u66fc\u4e0d\u52d5\u687f\u83cc-\u918b\u9178\u9223\u4e0d\u52d5\u687f\u83cc\u5fa9\u5408\u9ad4\u654f\u611f\u5206\u96e2\u682a\u5f15\u8d77\u611f\u67d3\u7684NDA\uff0c\u6709\u671b\u65bc2024\u5e74\u7372NMPA\u6279\u51c6\u3002<\/li>\n<\/ul>\n<p><b>ZL-1102 (IL-17 Humabody<sup>\u00ae<\/sup>)<\/b><\/p>\n<ul type=\"disc\">\n<li>\u518d\u9f0e\u91ab\u85e5\u5c07\u65bc2024\u5e74\u555f\u52d5\u91dd\u5c0d\u6162\u6027\u6591\u584a\u72c0\u9280\u5c51\u75c5\u7684\u5168\u74032\u671f\u7814\u7a76\u3002<\/li>\n<\/ul>\n<p>\u00a0<b><u>\u96fb\u8a71\u6703\u8b70\u548c\u7db2\u7d61\u76f4\u64ad\u76f8\u95dc\u4fe1\u606f<\/u><\/b><\/p>\n<p>\u518d\u9f0e\u91ab\u85e5\u5c07\u65bc\u7f8e\u570b\u6771\u90e8\u6642\u95932023\u5e7411\u67088\u65e5\u4e0a\u53488\u9ede\u8209\u884c\u96fb\u8a71\u6703\u8b70\u548c\u7db2\u7d61\u76f4\u64ad\u3002\u8207\u6703\u8005\u53ef\u4ee5\u8a2a\u554f\u516c\u53f8\u7db2\u7ad9 <a href=\"http:\/\/ir.zailaboratory.com\/\" target=\"_blank\" rel=\"nofollow noopener\">http:\/\/ir.zailaboratory.com<\/a> \u53c3\u8207\u5be6\u6642\u7db2\u7d61\u76f4\u64ad\u3002\u5982\u8981\u53c3\u52a0\u96fb\u8a71\u6703\u8b70\uff0c\u9700\u63d0\u524d\u6ce8\u518a\u3002<\/p>\n<p>\u8a73\u7d30\u4fe1\u606f\u5982\u4e0b\uff1a<\/p>\n<p>\u6ce8\u518a\u93c8\u63a5\uff1a<a href=\"https:\/\/register.vevent.com\/register\/BI87a7a83f6a6441279fddbaae217dd092\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/register.vevent.com\/register\/BI87a7a83f6a6441279fddbaae217dd092<\/a> 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