{"id":104367,"date":"2023-12-08T12:10:00","date_gmt":"2023-12-08T04:10:00","guid":{"rendered":"https:\/\/gothe.tw\/?p=104367"},"modified":"2023-12-08T12:10:00","modified_gmt":"2023-12-08T04:10:00","slug":"%e5%9f%ba%e7%9f%b3%e8%97%a5%e6%a5%ad%e5%ae%a3%e5%b8%83%e6%93%87%e6%8d%b7%e7%be%8e%ef%bc%88%e8%88%92%e6%a0%bc%e5%88%a9%e5%96%ae%e6%8a%97%e6%b3%a8%e5%b0%84%e6%b6%b2%ef%bc%89%e4%b8%80%e7%b7%9a","status":"publish","type":"post","link":"https:\/\/gothe.tw\/?p=104367","title":{"rendered":"\u57fa\u77f3\u85e5\u696d\u5ba3\u5e03\u64c7\u6377\u7f8e\u00ae\uff08\u8212\u683c\u5229\u55ae\u6297\u6ce8\u5c04\u6db2\uff09\u4e00\u7dda\u6cbb\u7642\u98df\u7ba1\u9c57\u764c\u7684\u65b0\u9069\u61c9\u75c7\u5728\u4e2d\u570b\u7372\u6279"},"content":{"rendered":"<div>\n<div>\n<ul 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\u548c\u7e3d\u751f\u5b58\u671f\uff08OS\uff09\uff0c\u6b21\u8981\u7814\u7a76\u7d42\u9ede\u5305\u62ec\u7814\u7a76\u8005\u8a55\u4f30\u7684PFS\u3001BICR\u548c\u7814\u7a76\u8005\u8a55\u4f30\u7684\u5ba2\u89c0\u7de9\u89e3\u7387\uff08ORR\uff09\u53ca\u7de9\u89e3\u6301\u7e8c\u6642\u9593\uff08DoR\uff09\u7b49\u3002<\/p>\n<p>\u6b64\u524d\uff0cGEMSTONE-304\u7814\u7a76\u6578\u64da\u5df2\u57282023\u5e74ESMO\u4e16\u754c\u80c3\u8178\u9053\u816b\u7624\u5927\u6703\uff08ESMO GI 2023\uff09 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5.4\u500b\u6708\uff0c\u98a8\u96aa\u6bd4\uff08HR\uff09=0.67 (95% CI, 0.54-0.82)\uff0cP\u503c=0.0002\u3002\u64c7\u6377\u7f8e<sup>\u00ae<\/sup>\u6cbb\u7642\u7d44\u8207\u5b89\u6170\u5291\u7d44\u60a3\u8005\u4e2d\u4f4dOS\u70ba15.3\u500b\u6708vs 11.5\u500b\u6708\uff0cHR=0.70 (95% CI, 0.55-0.90)\u00a0\uff0cP\u503c=0.0076\u3002\u4e9e\u7d44\u5206\u6790\u986f\u793a\uff0cPD-L1\u8868\u9054\u72c0\u614b\u7b49\u5404\u9810\u8a2d\u4e9e\u7d44\u548c\u7e3d\u9ad4\u4eba\u7fa4\u7684\u7372\u76ca\u8da8\u52e2\u57fa\u672c\u4e00\u81f4\u3002BICR\u8a55\u4f30\u7684ORR\u70ba60.1% vs 45.2%\uff0c\u5dee\u503c\u70ba14.9%\uff1bDoR\u70ba6.0\u500b\u6708 vs 4.5\u500b\u6708\u3002<\/p>\n<p><b>\u95dc\u65bc\u98df\u7ba1\u764c<\/b><\/p>\n<p>\u98df\u7ba1\u764c\u662f\u5168\u7403\u5e38\u898b\u7684\u764c\u75c7\u4e4b\u4e00\uff0c\u64daGLOBOCAN 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href=\"http:\/\/www.cstonepharma.com\/\" target=\"_blank\" rel=\"nofollow 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